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The interface of condensates of the hnRNPA1 low-complexity domain promotes formation of amyloid fibrils

The maturation of liquid-like protein condensates into amyloid fibrils has been associated with several neurodegenerative diseases. However, the molecular mechanisms underlying this liquid-to-solid transition have remained largely unclear. Here we analyse the amyloid formation mediated by condensati...

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Detalles Bibliográficos
Autores principales:	Linsenmeier, Miriam, Faltova, Lenka, Morelli, Chiara, Capasso Palmiero, Umberto, Seiffert, Charlotte, Küffner, Andreas M., Pinotsi, Dorothea, Zhou, Jiangtao, Mezzenga, Raffaele, Arosio, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533390/ https://www.ncbi.nlm.nih.gov/pubmed/37749234 http://dx.doi.org/10.1038/s41557-023-01289-9

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