Cargando…
Site-specific bioorthogonal protein labelling by tetrazine ligation using endogenous β-amino acid dienophiles
The tetrazine ligation is an inverse electron-demand Diels–Alder reaction widely used for bioorthogonal modifications due to its versatility, site specificity and fast reaction kinetics. A major limitation has been the incorporation of dienophiles in biomolecules and organisms, which relies on exter...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533398/ https://www.ncbi.nlm.nih.gov/pubmed/37400596 http://dx.doi.org/10.1038/s41557-023-01252-8 |