Transgenic ferret models define pulmonary ionocyte diversity and function

Speciation leads to adaptive changes in organ cellular physiology and creates challenges for studying rare cell-type functions that diverge between humans and mice. Rare cystic fibrosis transmembrane conductance regulator (CFTR)-rich pulmonary ionocytes exist throughout the cartilaginous airways of...

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Detalles Bibliográficos
Autores principales: Yuan, Feng, Gasser, Grace N., Lemire, Evan, Montoro, Daniel T., Jagadeesh, Karthik, Zhang, Yan, Duan, Yifan, Ievlev, Vitaly, Wells, Kristen L., Rotti, Pavana G., Shahin, Weam, Winter, Michael, Rosen, Bradley H., Evans, Idil, Cai, Qian, Yu, Miao, Walsh, Susan A., Acevedo, Michael R., Pandya, Darpan N., Akurathi, Vamsidhar, Dick, David W., Wadas, Thaddeus J., Joo, Nam Soo, Wine, Jeffrey J., Birket, Susan, Fernandez, Courtney M., Leung, Hui Min, Tearney, Guillermo J., Verkman, Alan S., Haggie, Peter M., Scott, Kathleen, Bartels, Douglas, Meyerholz, David K., Rowe, Steven M., Liu, Xiaoming, Yan, Ziying, Haber, Adam L., Sun, Xingshen, Engelhardt, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533402/
https://www.ncbi.nlm.nih.gov/pubmed/37730992
http://dx.doi.org/10.1038/s41586-023-06549-9

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