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Genetic and clinical variables act synergistically to impact neurodevelopmental outcomes in children with single ventricle heart disease
BACKGROUND: Recent large-scale sequencing efforts have shed light on the genetic contribution to the etiology of congenital heart defects (CHD); however, the relative impact of genetics on clinical outcomes remains less understood. Outcomes analyses using genetics are complicated by the intrinsic se...
Autores principales: | Miller, Thomas A., Hernandez, Edgar J., Gaynor, J. William, Russell, Mark W., Newburger, Jane W., Chung, Wendy, Goldmuntz, Elizabeth, Cnota, James F., Zyblewski, Sinai C., Mahle, William T., Zak, Victor, Ravishankar, Chitra, Kaltman, Jonathan R., McCrindle, Brian W., Clarke, Shanelle, Votava-Smith, Jodie K., Graham, Eric M., Seed, Mike, Rudd, Nancy, Bernstein, Daniel, Lee, Teresa M., Yandell, Mark, Tristani-Firouzi, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533527/ https://www.ncbi.nlm.nih.gov/pubmed/37758840 http://dx.doi.org/10.1038/s43856-023-00361-2 |
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