Ceramide synthase CERS4 gene downregulation is associated with KRAS mutation in colorectal cancer

Ceramide, the central molecule in sphingolipid synthesis, is a bioactive lipid that serves as a regulatory molecule in the anti-inflammatory responses, apoptosis, programmed necrosis, autophagy, and cell motility of cancer cells. In particular, the authors have reported differences in sphingolipid c...

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Detalles Bibliográficos
Autores principales: Hayama, Tamuro, Hama, Kotaro, Ozawa, Tsuyoshi, Fujiwara, Yuko, Nozawa, Keijiro, Matsuda, Keiji, Yokoyama, Kazuaki, Hashiguchi, Yojiro, Ochiai, Hiroki, Misawa, Takeyuki, Fukagawa, Takeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533536/
https://www.ncbi.nlm.nih.gov/pubmed/37758931
http://dx.doi.org/10.1038/s41598-023-43557-1

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