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Why anticoagulant studies on sepsis fail frequently --- start with SCARLET

The Sepsis Coagulopathy Asahi Recombinant LE Thrombomodulin (SCARLET) trial has many defects, and thus cannot be the terminator of recombinant thrombomodulin (rTM). On the contrary, it provides sufficient evidence for further research. Based on analysis focusing on the failure of SCARLET and several...

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Detalles Bibliográficos
Autores principales: Guo, Jian-Ying, Lin, Hong-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533541/
https://www.ncbi.nlm.nih.gov/pubmed/37321903
http://dx.doi.org/10.1016/j.cjtee.2023.04.006