Multimodal analysis of cell-free DNA whole-methylome sequencing for cancer detection and localization

Multimodal epigenetic characterization of cell-free DNA (cfDNA) could improve the performance of blood-based early cancer detection. However, integrative profiling of cfDNA methylome and fragmentome has been technologically challenging. Here, we adapt an enzyme-mediated methylation sequencing method...

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Detalles Bibliográficos
Autores principales: Bie, Fenglong, Wang, Zhijie, Li, Yulong, Guo, Wei, Hong, Yuanyuan, Han, Tiancheng, Lv, Fang, Yang, Shunli, Li, Suxing, Li, Xi, Nie, Peiyao, Xu, Shun, Zang, Ruochuan, Zhang, Moyan, Song, Peng, Feng, Feiyue, Duan, Jianchun, Bai, Guangyu, Li, Yuan, Huai, Qilin, Zhou, Bolun, Huang, Yu S., Chen, Weizhi, Tan, Fengwei, Gao, Shugeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533817/
https://www.ncbi.nlm.nih.gov/pubmed/37758728
http://dx.doi.org/10.1038/s41467-023-41774-w

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