Cargando…

DNA methylation at quantitative trait loci (mQTLs) varies with cell type and nonheritable factors and may improve breast cancer risk assessment

To individualise breast cancer (BC) prevention, markers to follow a person’s changing environment and health extending beyond static genetic risk scores are required. Here, we analysed cervical and breast DNA methylation (n = 1848) and single nucleotide polymorphisms (n = 1442) and demonstrate that...

Descripción completa

Detalles Bibliográficos
Autores principales: Herzog, Chiara, Jones, Allison, Evans, Iona, Zikan, Michal, Cibula, David, Harbeck, Nadia, Colombo, Nicoletta, Rådestad, Angelique Flöter, Gemzell-Danielsson, Kristina, Pashayan, Nora, Widschwendter, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533818/
https://www.ncbi.nlm.nih.gov/pubmed/37758816
http://dx.doi.org/10.1038/s41698-023-00452-2