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Early breast cancer detection and differentiation tool based on tissue impedance characteristics and machine learning

During Basic screening, it is challenging, if not impossible to detect breast cancer especially in the earliest stage of tumor development. However, measuring the electrical impedance of biological tissue can detect abnormalities even before being palpable. Thus, we used impedance characteristics da...

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Autores principales: Salem, Soumaya Ben, Ali, Samar Zahra, Leo, Anyik John, Lachiri, Zied, Mkandawire, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534039/
https://www.ncbi.nlm.nih.gov/pubmed/37780837
http://dx.doi.org/10.3389/frai.2023.1248977
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author Salem, Soumaya Ben
Ali, Samar Zahra
Leo, Anyik John
Lachiri, Zied
Mkandawire, Martin
author_facet Salem, Soumaya Ben
Ali, Samar Zahra
Leo, Anyik John
Lachiri, Zied
Mkandawire, Martin
author_sort Salem, Soumaya Ben
collection PubMed
description During Basic screening, it is challenging, if not impossible to detect breast cancer especially in the earliest stage of tumor development. However, measuring the electrical impedance of biological tissue can detect abnormalities even before being palpable. Thus, we used impedance characteristics data of various breast tissue to develop a breast cancer screening tool guided and augmented by a deep learning (DL). A DL algorithm was trained to ideally classify six classes of breast cancer based on electrical impedance characteristics data of the breast tissue. The tool correctly predicted breast cancer in data of patients whose breast tissue impedance was reported to have been measured when other methods detected no anomaly in the tissue. Furthermore, a DL-based approach using Long Short-Term Memory (LSTM) effectively classified breast tissue with an accuracy of 96.67%. Thus, the DL algorithm and method we developed accurately augmented breast tissue classification using electrical impedance and enhanced the ability to detect and differentiate cancerous tissue in very early stages. However, more data and pre-clinical is required to improve the accuracy of this early breast cancer detection and differentiation tool.
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spelling pubmed-105340392023-09-29 Early breast cancer detection and differentiation tool based on tissue impedance characteristics and machine learning Salem, Soumaya Ben Ali, Samar Zahra Leo, Anyik John Lachiri, Zied Mkandawire, Martin Front Artif Intell Artificial Intelligence During Basic screening, it is challenging, if not impossible to detect breast cancer especially in the earliest stage of tumor development. However, measuring the electrical impedance of biological tissue can detect abnormalities even before being palpable. Thus, we used impedance characteristics data of various breast tissue to develop a breast cancer screening tool guided and augmented by a deep learning (DL). A DL algorithm was trained to ideally classify six classes of breast cancer based on electrical impedance characteristics data of the breast tissue. The tool correctly predicted breast cancer in data of patients whose breast tissue impedance was reported to have been measured when other methods detected no anomaly in the tissue. Furthermore, a DL-based approach using Long Short-Term Memory (LSTM) effectively classified breast tissue with an accuracy of 96.67%. Thus, the DL algorithm and method we developed accurately augmented breast tissue classification using electrical impedance and enhanced the ability to detect and differentiate cancerous tissue in very early stages. However, more data and pre-clinical is required to improve the accuracy of this early breast cancer detection and differentiation tool. Frontiers Media S.A. 2023-09-13 /pmc/articles/PMC10534039/ /pubmed/37780837 http://dx.doi.org/10.3389/frai.2023.1248977 Text en Copyright © 2023 Salem, Ali, Leo, Lachiri and Mkandawire. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Artificial Intelligence
Salem, Soumaya Ben
Ali, Samar Zahra
Leo, Anyik John
Lachiri, Zied
Mkandawire, Martin
Early breast cancer detection and differentiation tool based on tissue impedance characteristics and machine learning
title Early breast cancer detection and differentiation tool based on tissue impedance characteristics and machine learning
title_full Early breast cancer detection and differentiation tool based on tissue impedance characteristics and machine learning
title_fullStr Early breast cancer detection and differentiation tool based on tissue impedance characteristics and machine learning
title_full_unstemmed Early breast cancer detection and differentiation tool based on tissue impedance characteristics and machine learning
title_short Early breast cancer detection and differentiation tool based on tissue impedance characteristics and machine learning
title_sort early breast cancer detection and differentiation tool based on tissue impedance characteristics and machine learning
topic Artificial Intelligence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534039/
https://www.ncbi.nlm.nih.gov/pubmed/37780837
http://dx.doi.org/10.3389/frai.2023.1248977
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