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AFsample: improving multimer prediction with AlphaFold using massive sampling
SUMMARY: The AlphaFold2 neural network model has revolutionized structural biology with unprecedented performance. We demonstrate that by stochastically perturbing the neural network by enabling dropout at inference combined with massive sampling, it is possible to improve the quality of the generat...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534052/ https://www.ncbi.nlm.nih.gov/pubmed/37713472 http://dx.doi.org/10.1093/bioinformatics/btad573 |