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cloneRate: fast estimation of single-cell clonal dynamics using coalescent theory
MOTIVATION: While evolutionary approaches to medicine show promise, measuring evolution itself is difficult due to experimental constraints and the dynamic nature of body systems. In cancer evolution, continuous observation of clonal architecture is impossible, and longitudinal samples from multiple...
Autores principales: | Johnson, Brian, Shuai, Yubo, Schweinsberg, Jason, Curtius, Kit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534056/ https://www.ncbi.nlm.nih.gov/pubmed/37699006 http://dx.doi.org/10.1093/bioinformatics/btad561 |
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