UPLC-Q-TOF/MS-based metabonomics reveals mechanisms for Holothuria leucospilota polysaccharides (HLP)-regulated serum metabolic changes in diabetic rats

This study aimed to use metabolomic methods to explore how Holothuria leucospilota polysaccharides (HLP) improved metabolism disorders in the liver of Goto-Kakizaki (GK) rats with spontaneous type 2 diabetes. The results showed that HLP effectively improved the metabolic disorder. Based on KEGG func...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Zhao, Fuqiang, Ma, Tingting, Zheng, Yuanping, Cao, Jun, Li, Chuan, Zhu, Kexue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article(s) from the Special Issue on Marine Lipids by Dr. Alan Carne, Dr. Haizhou Wu, Dr. Alaa El-Din Bekhit and Dr. Mirja Ahmmed
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534105/
https://www.ncbi.nlm.nih.gov/pubmed/37780338
http://dx.doi.org/10.1016/j.fochx.2023.100741

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