PER2/P65-driven glycogen synthase 1 transcription in macrophages modulates gut inflammation and pathogenesis of rectal prolapse

Rectal prolapse in serious inflammatory bowel disease is caused by abnormal reactions of the intestinal mucosal immune system. The circadian clock has been implicated in immune defense and inflammatory responses, but the mechanisms by which it regulates gut inflammation remain unclear. In this study...

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Detalles Bibliográficos
Autores principales: Ding, Zhao, Ge, Wenhao, Xu, Xiaodong, Xu, Xi, Wang, Shiming, Zhang, Jianfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534228/
https://www.ncbi.nlm.nih.gov/pubmed/37660913
http://dx.doi.org/10.1016/j.jbc.2023.105219

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