Pirh2-dependent DNA damage in neurons induced by the G-quadruplex ligand pyridostatin

Noncanonical base pairing between four guanines (G) within single-stranded G-rich sequences leads to formation of а G-quartet. Self-stacking of G-quartets results in a columnar four-stranded DNA structure known as the G-quadruplex (G4 or G4-DNA). In cancer cells, G4-DNA regulates multiple DNA-depend...

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Detalles Bibliográficos
Autores principales: Escarcega, Rocio Diaz, Patil, Abhijeet A., Moruno-Manchon, Jose F., Urayama, Akihiko, Marrelli, Sean P., Kim, Nayun, Monchaud, David, McCullough, Louise D., Tsvetkov, Andrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534229/
https://www.ncbi.nlm.nih.gov/pubmed/37579947
http://dx.doi.org/10.1016/j.jbc.2023.105157

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