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Constructing an artificial short route for cell-free biosynthesis of the phenethylisoquinoline scaffold
Plant-originated natural products are important drug sources. However, total biosynthesis of these compounds is often not achievable due to their uncharacterized, lengthy biosynthetic pathways. In nature, phenethylisoquinoline alkaloids (PIAs) such as colchicine are biosynthesized via a common precu...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
KeAi Publishing
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534260/ https://www.ncbi.nlm.nih.gov/pubmed/37781172 http://dx.doi.org/10.1016/j.synbio.2023.09.003 |