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Phenotypic and Genomic Characteristics of Campylobacter gastrosuis sp. nov. Isolated from the Stomachs of Pigs in Beijing

Campylobacter is among the four main causes of gastroenteritis worldwide. Most reported Campylobacter infections are caused by C. jejuni and C. coli. However, other emerging Campylobacter pathogens have been recognized as important pathogens in humans and animals. A novel bacterial strain, PS10(T),...

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Autores principales: Wang, Hairui, Gu, Yixin, He, Lihua, Sun, Lu, Zhou, Guilan, Chen, Xiaoli, Zhang, Xin, Shao, Zhujun, Zhang, Jianzhong, Zhang, Maojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534318/
https://www.ncbi.nlm.nih.gov/pubmed/37764121
http://dx.doi.org/10.3390/microorganisms11092278
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author Wang, Hairui
Gu, Yixin
He, Lihua
Sun, Lu
Zhou, Guilan
Chen, Xiaoli
Zhang, Xin
Shao, Zhujun
Zhang, Jianzhong
Zhang, Maojun
author_facet Wang, Hairui
Gu, Yixin
He, Lihua
Sun, Lu
Zhou, Guilan
Chen, Xiaoli
Zhang, Xin
Shao, Zhujun
Zhang, Jianzhong
Zhang, Maojun
author_sort Wang, Hairui
collection PubMed
description Campylobacter is among the four main causes of gastroenteritis worldwide. Most reported Campylobacter infections are caused by C. jejuni and C. coli. However, other emerging Campylobacter pathogens have been recognized as important pathogens in humans and animals. A novel bacterial strain, PS10(T), was isolated from the gastric mucous of pigs in 2022 in Beijing, China. The cell was Gram-negative, microaerobic, motile, and negative for catalase, oxidase, and urease. Phylogenetic and phylogenomic analyses based on the 16S rRNA gene and core genome indicated that this isolate belongs to the genus Campylobacter. There were low dDDH relatedness and ANI values shared within this strain and its closest species C. mucosalis below the cut-off values generally recognized for isolates of the same species. The draft genome size of PS10(T) is 2,240,910 bp in length with a percentage of DNA G+C contents of 37.72%. Comparing the phenotypic and phylogenetic features among this isolate and its related organisms, strain PS10(T) represents a novel species within the genus Campylobacter, for which the name Campylobacter gastrosuis sp. nov. (Type strain PS10(T) = GDMCC 1.3686(T) = JCM 35849(T)) is proposed.
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spelling pubmed-105343182023-09-29 Phenotypic and Genomic Characteristics of Campylobacter gastrosuis sp. nov. Isolated from the Stomachs of Pigs in Beijing Wang, Hairui Gu, Yixin He, Lihua Sun, Lu Zhou, Guilan Chen, Xiaoli Zhang, Xin Shao, Zhujun Zhang, Jianzhong Zhang, Maojun Microorganisms Article Campylobacter is among the four main causes of gastroenteritis worldwide. Most reported Campylobacter infections are caused by C. jejuni and C. coli. However, other emerging Campylobacter pathogens have been recognized as important pathogens in humans and animals. A novel bacterial strain, PS10(T), was isolated from the gastric mucous of pigs in 2022 in Beijing, China. The cell was Gram-negative, microaerobic, motile, and negative for catalase, oxidase, and urease. Phylogenetic and phylogenomic analyses based on the 16S rRNA gene and core genome indicated that this isolate belongs to the genus Campylobacter. There were low dDDH relatedness and ANI values shared within this strain and its closest species C. mucosalis below the cut-off values generally recognized for isolates of the same species. The draft genome size of PS10(T) is 2,240,910 bp in length with a percentage of DNA G+C contents of 37.72%. Comparing the phenotypic and phylogenetic features among this isolate and its related organisms, strain PS10(T) represents a novel species within the genus Campylobacter, for which the name Campylobacter gastrosuis sp. nov. (Type strain PS10(T) = GDMCC 1.3686(T) = JCM 35849(T)) is proposed. MDPI 2023-09-10 /pmc/articles/PMC10534318/ /pubmed/37764121 http://dx.doi.org/10.3390/microorganisms11092278 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wang, Hairui
Gu, Yixin
He, Lihua
Sun, Lu
Zhou, Guilan
Chen, Xiaoli
Zhang, Xin
Shao, Zhujun
Zhang, Jianzhong
Zhang, Maojun
Phenotypic and Genomic Characteristics of Campylobacter gastrosuis sp. nov. Isolated from the Stomachs of Pigs in Beijing
title Phenotypic and Genomic Characteristics of Campylobacter gastrosuis sp. nov. Isolated from the Stomachs of Pigs in Beijing
title_full Phenotypic and Genomic Characteristics of Campylobacter gastrosuis sp. nov. Isolated from the Stomachs of Pigs in Beijing
title_fullStr Phenotypic and Genomic Characteristics of Campylobacter gastrosuis sp. nov. Isolated from the Stomachs of Pigs in Beijing
title_full_unstemmed Phenotypic and Genomic Characteristics of Campylobacter gastrosuis sp. nov. Isolated from the Stomachs of Pigs in Beijing
title_short Phenotypic and Genomic Characteristics of Campylobacter gastrosuis sp. nov. Isolated from the Stomachs of Pigs in Beijing
title_sort phenotypic and genomic characteristics of campylobacter gastrosuis sp. nov. isolated from the stomachs of pigs in beijing
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534318/
https://www.ncbi.nlm.nih.gov/pubmed/37764121
http://dx.doi.org/10.3390/microorganisms11092278
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