Cargando…

Bedaquiline-Loaded Solid Lipid Nanoparticles Drug Delivery in the Management of Non-Small-Cell Lung Cancer (NSCLC)

Non-small-cell lung cancer (NSCLC) mortality and new case rates are both on the rise. Most patients have fewer treatment options accessible due to side effects from drugs and the emergence of drug resistance. Bedaquiline (BQ), a drug licensed by the FDA to treat tuberculosis (TB), has demonstrated h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Najib Ullah, Shehla Nasar Mir, Afzal, Obaid, Altamimi, Abdulmalik Saleh Alfawaz, Alossaimi, Manal A., Almalki, Waleed H, Alzahrani, Abdulaziz, Barkat, Md. Abul, Almeleebia, Tahani M., Alshareef, Hanan, Shorog, Eman M., Khan, Gyas, Singh, Tanuja, Singh, J. K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534335/ https://www.ncbi.nlm.nih.gov/pubmed/37765117 http://dx.doi.org/10.3390/ph16091309

Ejemplares similares

Emergence of Nano-Based Formulations for Effective Delivery of Flavonoids against Topical Infectious Disorders
por: Dwivedi, Khusbu, et al.
Publicado: (2023)

Nanomedicine in the Management of Alzheimer’s Disease: State-of-the-Art
por: Mir Najib Ullah, Shehla Nasar, et al.
Publicado: (2023)

Preparation, Characterization, and Evaluation of Curcumin–Graphene Oxide Complex-Loaded Liposomes against Staphylococcus aureus in Topical Disease
por: Rahman, Mahfoozur, et al.
Publicado: (2022)

Design, Synthesis, ADME, and Anticancer Studies of Newer N-Aryl-5-(3,4,5-Trifluorophenyl)-1,3,4-Oxadiazol-2-Amines: An Insight into Experimental and Theoretical Investigations
por: Agarwal, Mohit, et al.
Publicado: (2023)

Design-of-Experiment-Assisted Fabrication of Biodegradable Polymeric Nanoparticles: In Vitro Characterization, Biological Activity, and In Vivo Assessment
por: Mir, Mushtaq Ahmad, et al.
Publicado: (2023)

Resveratrol-Loaded Chia Seed Oil-Based Nanogel as an Anti-Inflammatory in Adjuvant-Induced Arthritis
por: Afzal, Obaid, et al.
Publicado: (2023)

Synthesis and Anticancer Evaluation of 4-Chloro-2-((5-aryl-1,3,4-oxadiazol-2-yl)amino)phenol Analogues: An Insight into Experimental and Theoretical Studies
por: Afzal, Obaid, et al.
Publicado: (2023)

Cationic Solid Lipid Nanoparticles of Resveratrol for Hepatocellular Carcinoma Treatment: Systematic Optimization, in vitro Characterization and Preclinical Investigation
por: Rahman, Mahfoozur, et al.
Publicado: (2020)

Superficial Dermatophytosis across the World’s Populations: Potential Benefits from Nanocarrier-Based Therapies and Rising Challenges
por: Keshwania, Puja, et al.
Publicado: (2023)

Analysis of Anti-Arrhythmic Impacts of Crocin through Estimation of Expression of Cx43 in Myocardial Infarction Using a Rat Animal Model
por: Li, Huan, et al.
Publicado: (2022)

Natural Oils Enhance the Topical Delivery of Ketoconazole by Nanoemulgel for Fungal Infections
por: Ahmad, Irfan, et al.
Publicado: (2023)

Drug Delivery Challenges and Current Progress in Nanocarrier-Based Ocular Therapeutic System
por: Akhter, Md Habban, et al.
Publicado: (2022)

Hispolon-Loaded Liquid Crystalline Nanoparticles: Development, Stability, In Vitro Delivery Profile, and Assessment of Hepatoprotective Activity in Hepatocellular Carcinoma
por: Ansari, Mohammad Javed, et al.
Publicado: (2022)

Exploring Nanocarriers as Treatment Modalities for Skin Cancer
por: Adnan, Mohammad, et al.
Publicado: (2023)

Crotamiton-loaded tea tree oil containing phospholipid-based microemulsion hydrogel for scabies treatment: in vitro, in vivo evaluation, and dermatokinetic studies
por: Chen, Lihua, et al.
Publicado: (2021)

Improved Subcutaneous Delivery of Ketoconazole Using EpiDerm and HSPiP Software-Based Simulations as Assessed by Cell Viability, Cellular Uptake, Permeation, and Hemolysis In Vitro Studies
por: Hussain, Afzal, et al.
Publicado: (2022)

Impact of Composition and Morphology of Ketoconazole-Loaded Solid Lipid Nanoparticles on Intestinal Permeation and Gastroplus-Based Prediction Studies
por: Aljurbui, Shaya Jubran, et al.
Publicado: (2022)

Preferential Solvation Study of Rosuvastatin in the {PEG400 (1) + Water (2)} Cosolvent Mixture and GastroPlus Software-Based In Vivo Predictions
por: Hussain, Afzal, et al.
Publicado: (2023)

Analgesic and Anticancer Activity of Benzoxazole Clubbed 2-Pyrrolidinones as Novel Inhibitors of Monoacylglycerol Lipase
por: Afzal, Obaid, et al.
Publicado: (2021)

Ameliorative Effect of Ethanolic Extract of Moringa oleifera Leaves in Combination with Curcumin against PTZ-Induced Kindled Epilepsy in Rats: In Vivo and In Silico
por: Alam, Md. Niyaz, et al.
Publicado: (2023)

A Novel Quantum Dots-Based Fluorescent Sensor for Determination of the Anticancer Dacomitinib: Application to Dosage Forms
por: Alossaimi, Manal A., et al.
Publicado: (2023)

Synthesis, Anticancer Activity, and In Silico Studies of 5-(3-Bromophenyl)-N-aryl-4H-1,2,4-triazol-3-amine Analogs
por: Ahsan, Mohamed Jawed, et al.
Publicado: (2023)

Baicalin-Loaded Lipid–Polymer Hybrid Nanoparticles Inhibiting the Proliferation of Human Colon Cancer: Pharmacokinetics and In Vivo Evaluation
por: Riadi, Yassine, et al.
Publicado: (2023)

Trastuzumab-Mediated Cardiotoxicity and Its Preventive Intervention by Zingerone through Antioxidant and Inflammatory Pathway in Rats
por: Khan, Gyas, et al.
Publicado: (2023)

Mechanistic of Vesicular Ethosomes and Elastic Liposomes on Permeation Profiles of Acyclovir across Artificial Membrane, Human Cultured EpiDerm, and Rat Skin: In Vitro-Ex Vivo Study
por: Hussain, Afzal, et al.
Publicado: (2023)

Cardioprotective Effect of Tangeretin by Inhibiting PTEN/AKT/mTOR Axis in Experimental Sepsis-Induced Myocardial Dysfunction
por: Shiroorkar, Predeepkumar Narayanappa, et al.
Publicado: (2020)

A β–Sitosterol Encapsulated Biocompatible Alginate/Chitosan Polymer Nanocomposite for the Treatment of Breast Cancer
por: Afzal, Obaid, et al.
Publicado: (2022)

Gut Microbiota Disruption in COVID-19 or Post-COVID Illness Association with severity biomarkers: A Possible Role of Pre / Pro-biotics in manipulating microflora
por: Alharbi, Khalid Saad, et al.
Publicado: (2022)

Thymoquinone Induced Leishmanicidal Effect via Programmed Cell Death in Leishmania donovani
por: Islamuddin, Mohammad, et al.
Publicado: (2022)

Pyrazoline Containing Compounds as Therapeutic Targets for Neurodegenerative Disorders
por: Ahsan, Mohamed Jawed, et al.
Publicado: (2022)

Novel and Potential Small Molecule Scaffolds as DYRK1A Inhibitors by Integrated Molecular Docking-Based Virtual Screening and Dynamics Simulation Study
por: Shahroz, Mir Mohammad, et al.
Publicado: (2022)

Design, Synthesis, In Vivo, and In Silico Evaluation of Benzothiazoles Bearing a 1,3,4-Oxadiazole Moiety as New Antiepileptic Agents
por: Chauhan, Bharti, et al.
Publicado: (2023)

Inhibition of Chikungunya Virus Infection by 4-Hydroxy-1-Methyl-3-(3-morpholinopropanoyl)quinoline-2(1H)-one (QVIR) Targeting nsP2 and E2 Proteins
por: Islamuddin, Mohammad, et al.
Publicado: (2021)

Butin Mitigates Memory Impairment in Streptozotocin-Induced Diabetic Rats by Inhibiting Oxidative Stress and Inflammatory Responses
por: Omer, Asma B., et al.
Publicado: (2022)

Determination of α1-acid glycoprotein (AGP) concentration by HPLC in patients following local infiltration analgesia for primary total hip arthroplasty and its relation to ropivacaine (total and unbound)
por: Abbas, Muhammad, et al.
Publicado: (2023)

A Prospective Study on Obstructive Sleep Apnea, Clinical Profile and Polysomnographic Variables
por: Kandasamy, Geetha, et al.
Publicado: (2023)

Acquired bedaquiline resistance in Karakalpakstan, Uzbekistan
por: Nair, P., et al.
Publicado: (2022)

Gingerol, a Natural Antioxidant, Attenuates Hyperglycemia and Downstream Complications
por: Alharbi, Khalid Saad, et al.
Publicado: (2022)

Neuroprotective Effect of Barbaloin on Streptozotocin-Induced Cognitive Dysfunction in Rats via Inhibiting Cholinergic and Neuroinflammatory Cytokines Pathway—TNF-α/IL-1β/IL-6/NF-κB
por: Omer, Asma B., et al.
Publicado: (2023)

Maleate salts of bedaquiline
por: Zeller, Matthias, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_blch58i0graeel6vr2n7lk5db7