Design and Synthesis of Novel 5-((3-(Trifluoromethyl)piperidin-1-yl)sulfonyl)indoline-2,3-dione Derivatives as Promising Antiviral Agents: In Vitro, In Silico, and Structure–Activity Relationship Studies

Herein, a series of new isatin derivatives was designed and synthesized (1–9) as broad-spectrum antiviral agents. Consequently, the antiviral activities of the synthesized compounds (1–9) were pursued against three viruses, namely influenza virus (H1N1), herpes simplex virus 1 (HSV-1), and coxsackie...

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Detalles Bibliográficos
Autores principales: Ezz Eldin, Rogy R., Saleh, Marwa A., Alwarsh, Sefat A., Rushdi, Areej, Althoqapy, Azza Ali, El Saeed, Hoda S., Abo Elmaaty, Ayman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534365/
https://www.ncbi.nlm.nih.gov/pubmed/37765055
http://dx.doi.org/10.3390/ph16091247

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