Cargando…

Current Advances in the Biosynthesis, Metabolism, and Transcriptional Regulation of α-Tomatine in Tomato

Steroid glycoalkaloids (SGAs) are a class of cholesterol-derived metabolites commonly found in the Solanaceae plants. α-Tomatine, a well-known bitter-tasting compound, is the major SGA in tomato, accumulating extensively in all plant tissues, particularly in the leaves and immature green fruits. α-T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yuanyuan, Hu, Hanru, Yang, Rujia, Zhu, Zhujun, Cheng, Kejun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534454/ https://www.ncbi.nlm.nih.gov/pubmed/37765452 http://dx.doi.org/10.3390/plants12183289

Ejemplares similares

Isomers of the Tomato Glycoalkaloids α-Tomatine and Dehydrotomatine: Relationship to Health Benefits
por: Kozukue, Nobuyuki, et al.
Publicado: (2023)

Total Phenolic, Flavonoid, Tomatine, and Tomatidine Contents and Antioxidant and Antimicrobial Activities of Extracts of Tomato Plant
por: Silva-Beltrán, Norma Patricia, et al.
Publicado: (2015)

In Vivo and in vitro antitumor activity of tomatine in hepatocellular carcinoma
por: Echeverría, Cesar, et al.
Publicado: (2022)

α-tomatine inhibits growth and induces apoptosis in HL-60 human myeloid leukemia cells
por: HUANG, HUARONG, et al.
Publicado: (2015)

Combination of α-Tomatine and Curcumin Inhibits Growth and Induces Apoptosis in Human Prostate Cancer Cells
por: Huang, Huarong, et al.
Publicado: (2015)

Mechanisms of growth inhibition of Phytomonas serpens by the alkaloids tomatine and tomatidine
por: Medina, Jorge Mansur, et al.
Publicado: (2015)

Tomatine Displays Antitumor Potential in In Vitro Models of Metastatic Melanoma
por: Serratì, Simona, et al.
Publicado: (2020)

The Effect of Tomatine on Gene Expression and Cell Monolayer Integrity in Caco-2
por: Arena, Mattia P., et al.
Publicado: (2018)

α-Tomatine-Mediated Anti-Cancer Activity In Vitro and In Vivo through Cell Cycle- and Caspase-Independent Pathways
por: Chao, Min-Wu, et al.
Publicado: (2012)

RNA-Seq Analyses of Midgut and Fat Body Tissues Reveal the Molecular Mechanism Underlying Spodoptera litura Resistance to Tomatine
por: Li, Qilin, et al.
Publicado: (2019)

Supramolecular Assembly of Hybrid Pt(II) Porphyrin/Tomatine Analogues with Different Nanostructures and Cytotoxic Activities
por: Fujitsuka, Mayuko, et al.
Publicado: (2021)

The cytotoxic effect of α-tomatine in MCF-7 human adenocarcinoma breast cancer cells depends on its interaction with cholesterol in incubation media and does not involve apoptosis induction
por: SUCHA, LENKA, et al.
Publicado: (2013)

Alpha-Tomatine Induces Apoptosis and Inhibits Nuclear Factor-Kappa B Activation on Human Prostatic Adenocarcinoma PC-3 Cells
por: Lee, Sui-Ting, et al.
Publicado: (2011)

Coordinated transcriptional regulation of the carotenoid biosynthesis contributes to fruit lycopene content in high-lycopene tomato genotypes
por: Duduit, James R, et al.
Publicado: (2022)

The structure, function and expression analysis of the nodulin 26-like intrinsic protein subfamily of plant aquaporins in tomato
por: Zhang, Yuxiang, et al.
Publicado: (2022)

Transcriptional regulation of oil biosynthesis in seed plants: Current understanding, applications, and perspectives
por: Yang, Yuzhou, et al.
Publicado: (2022)

Transcriptome Profiling of Tomato Fruit Development Reveals Transcription Factors Associated with Ascorbic Acid, Carotenoid and Flavonoid Biosynthesis
por: Ye, Jie, et al.
Publicado: (2015)

Tomatine Adjuvantation of Protective Immunity to a Major Pre-erythrocytic Vaccine Candidate of Malaria is Mediated via CD8(+) T Cell Release of IFN-γ
por: Heal, Karen G., et al.
Publicado: (2010)

Current Models for Transcriptional Regulation of Secondary Cell Wall Biosynthesis in Grasses
por: Rao, Xiaolan, et al.
Publicado: (2018)

Genetic dissection of vitamin E biosynthesis in tomato
por: Almeida, Juliana, et al.
Publicado: (2011)

The transcription factor AREB1 regulates primary metabolic pathways in tomato fruits
por: Bastías, Adriana, et al.
Publicado: (2014)

Overexpression of Sly-miR398b Compromises Disease Resistance against Botrytis cinerea through Regulating ROS Homeostasis and JA-Related Defense Genes in Tomato
por: Liu, Yuanyuan, et al.
Publicado: (2023)

Ripening-associated ethylene biosynthesis in tomato fruit is autocatalytically and developmentally regulated
por: Yokotani, Naoki, et al.
Publicado: (2009)

Jasmonate Positively Regulates Cold Tolerance by Promoting ABA Biosynthesis in Tomato
por: Ding, Fei, et al.
Publicado: (2022)

Tomato Cultivars Resistant or Susceptible to Spider Mites Differ in Their Biosynthesis and Metabolic Profile of the Monoterpenoid Pathway
por: Weinblum, Nati, et al.
Publicado: (2021)

Comprehensive Analysis of ABA Effects on Ethylene Biosynthesis and Signaling during Tomato Fruit Ripening
por: Mou, Wangshu, et al.
Publicado: (2016)

The paramutated SULFUREA locus of tomato is involved in auxin biosynthesis
por: Ehlert, Britta, et al.
Publicado: (2008)

Heterologous mogrosides biosynthesis in cucumber and tomato by genetic manipulation
por: Liao, Jingjing, et al.
Publicado: (2023)

Down-regulation of tomato PHYTOL KINASE strongly impairs tocopherol biosynthesis and affects prenyllipid metabolism in an organ-specific manner
por: Almeida, Juliana, et al.
Publicado: (2016)

Integrating Sugar Metabolism With Transport: Elevation of Endogenous Cell Wall Invertase Activity Up-Regulates SlHT2 and SlSWEET12c Expression for Early Fruit Development in Tomato
por: Ru, Lei, et al.
Publicado: (2020)

Recent Advances in the Transcriptional Regulation of Secondary Cell Wall Biosynthesis in the Woody Plants
por: Zhang, Jin, et al.
Publicado: (2018)

Alpha-Tomatine Attenuation of In Vivo Growth of Subcutaneous and Orthotopic Xenograft Tumors of Human Prostate Carcinoma PC-3 Cells Is Accompanied by Inactivation of Nuclear Factor-Kappa B Signaling
por: Lee, Sui-Ting, et al.
Publicado: (2013)

High Nitric Oxide Concentration Inhibits Photosynthetic Pigment Biosynthesis by Promoting the Degradation of Transcription Factor HY5 in Tomato
por: Wang, Lingyu, et al.
Publicado: (2022)

Regulation of Pyridine Nucleotide Metabolism During Tomato Fruit Development Through Transcript and Protein Profiling
por: Decros, Guillaume, et al.
Publicado: (2019)

The role of ABA in triggering ethylene biosynthesis and ripening of tomato fruit
por: Zhang, Mei, et al.
Publicado: (2009)

Ethylene independent induction of lycopene biosynthesis in tomato fruits by jasmonates
por: Liu, Lihong, et al.
Publicado: (2012)

Omics Analysis Unveils the Pathway Involved in the Anthocyanin Biosynthesis in Tomato Seedling and Fruits
por: He, Rui, et al.
Publicado: (2023)

Current Approaches for Advancement in Understanding the Molecular Mechanisms of Mycotoxin Biosynthesis
por: Gallo, Antonia, et al.
Publicado: (2021)

Editorial: Advances in tomato and tomato compounds research and technology
por: Pinela, José, et al.
Publicado: (2022)

Correction: Alpha-Tomatine Attenuation of In Vivo Growth of Subcutaneous and Orthotopic Xenograft Tumors of Human Prostate Carcinoma PC-3 Cells Is Accompanied by Inactivation of Nuclear Factor-Kappa B Signaling
por: Lee, Sui-Ting, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_fphbhcni4t7vdm3dtb5j2oaje4