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Novel Artificial Intelligence-Based Approaches for Ab Initio Structure Determination and Atomic Model Building for Cryo-Electron Microscopy

Single particle cryo-electron microscopy (cryo-EM) has emerged as the prevailing method for near-atomic structure determination, shedding light on the important molecular mechanisms of biological macromolecules. However, the inherent dynamics and structural variability of biological complexes couple...

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Detalles Bibliográficos
Autores principales: DiIorio, Megan C., Kulczyk, Arkadiusz W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534518/
https://www.ncbi.nlm.nih.gov/pubmed/37763837
http://dx.doi.org/10.3390/mi14091674