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Dynamic Monitoring of Intracellular Tacrolimus and Mycophenolic Acid Therapy in Renal Transplant Recipients Using Magnetic Bead Extraction Combined with LC-MS/MS

Background: Tacrolimus (TAC) and mycophenolic acid (MPA) are commonly used immunosuppressive therapies after renal transplant. Our objective was to quantify TAC and MPA concentrations in peripheral blood mononuclear cells (PBMCs) using liquid chromatography tandem mass spectrometry (LC-MS/MS) and to...

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Detalles Bibliográficos
Autores principales:	Xu, Huan, Liu, Yingying, Zhang, Yinan, Dai, Xinhua, Wang, Xueqiao, Chen, Haojun, Yan, Lin, Gong, Xingxin, Yue, Jiaxi, Wan, Zhengli, Fan, Jiwen, Bai, Yangjuan, Luo, Yao, Li, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534614/ https://www.ncbi.nlm.nih.gov/pubmed/37765287 http://dx.doi.org/10.3390/pharmaceutics15092318

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