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Atovaquone and Pibrentasvir Inhibit the SARS-CoV-2 Endoribonuclease and Restrict Infection In Vitro but Not In Vivo

The emergence of SARS-CoV-1 in 2003 followed by MERS-CoV and now SARS-CoV-2 has proven the latent threat these viruses pose to humanity. While the SARS-CoV-2 pandemic has shifted to a stage of endemicity, the threat of new coronaviruses emerging from animal reservoirs remains. To address this issue,...

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Detalles Bibliográficos
Autores principales: von Beck, Troy, Mena Hernandez, Luis, Zhou, Hongyi, Floyd, Katharine, Suthar, Mehul S., Skolnick, Jeffrey, Jacob, Joshy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534768/
https://www.ncbi.nlm.nih.gov/pubmed/37766247
http://dx.doi.org/10.3390/v15091841

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