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Single-Domain Antibody Multimers for Detection of Botulinum Neurotoxin Serotypes C, D, and Their Mosaics in Endopep-MS

Botulinum neurotoxins (BoNTs) are highly toxic proteins that require high-affinity immunocapture reagents for use in endopeptidase-based assays. Here, 30 novel and 2 earlier published llama single-domain antibodies (VHHs) against the veterinary-relevant BoNT serotypes C and D were yeast-produced. Th...

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Detalles Bibliográficos
Autores principales:	Harmsen, Michiel M., Cornelissen, Jan C., van der Wal, Fimme J., Bergervoet, Jan H. W., Koene, Miriam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535107/ https://www.ncbi.nlm.nih.gov/pubmed/37755999 http://dx.doi.org/10.3390/toxins15090573

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