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Identification of Acid Hydrolysis Metabolites of the Pimelea Toxin Simplexin for Targeted UPLC-MS/MS Analysis

Pimelea poisoning of cattle is a unique Australian toxic condition caused by the daphnane orthoester simplexin present in native Pimelea pasture plants. Rumen microorganisms have been proposed to metabolise simplexin by enzymatic reactions, likely at the orthoester and epoxide moieties of simplexin,...

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Detalles Bibliográficos
Autores principales:	Loh, Zhi Hung, Hungerford, Natasha L., Ouwerkerk, Diane, Klieve, Athol V., Fletcher, Mary T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535249/ https://www.ncbi.nlm.nih.gov/pubmed/37755977 http://dx.doi.org/10.3390/toxins15090551

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