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Development and Pharmacokinetic Evaluation of Novasomes for the Trans-nasal Delivery of Fluvoxamine Using Arachidonic Acid-Carboxymethyl Chitosan Conjugate

Depression is the major mental illness which causes along with loss of interest in daily life, a feeling of hopelessness, appetite or weight changes, anger and irritability. Due to the hepatic first-pass metabolism, the absolute bioavailability of fluvoxamine (FVM) after oral administration is about...

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Detalles Bibliográficos
Autores principales: Gulshan, Saima, Shah, Shahid, Shah, Pervaiz Akhtar, Irfan, Muhammad, Saadullah, Malik, Abbas, Ghulam, Hanif, Muhammad, Rasul, Akhtar, Ahmad, Nabeel, Mahmood, Abid, Basheer, Ejaz, Habib, Mohammad Omer, Alotaibi, Hadil Faris, Obaidullah, Ahmad J., Alsabhan, Jawza F., Alwassil, Osama l.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535484/
https://www.ncbi.nlm.nih.gov/pubmed/37765228
http://dx.doi.org/10.3390/pharmaceutics15092259