Cargando…
Fibrillization Process of Human Amyloid-Beta Protein (1–40) under a Molecular Crowding Environment Mimicking the Interior of Living Cells Using Cell Debris
Molecular crowding environments play a crucial role in understanding the mechanisms of biological reactions. Inside living cells, a diverse array of molecules coexists within a volume fraction ranging from 10% to 30% v/v. However, conventional spectroscopic methods often face difficulties in selecti...
Autores principales: | Hirai, Mitsuhiro, Arai, Shigeki, Iwase, Hiroki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535490/ https://www.ncbi.nlm.nih.gov/pubmed/37764331 http://dx.doi.org/10.3390/molecules28186555 |
Ejemplares similares
-
The Contrasting Effect of Macromolecular Crowding on Amyloid Fibril Formation
por: Ma, Qian, et al.
Publicado: (2012) -
Polyphenolic Biflavonoids Inhibit Amyloid-Beta Fibrillation and Disaggregate Preformed Amyloid-Beta Fibrils
por: Choi, Erika Y., et al.
Publicado: (2020) -
Rapid Conversion of Amyloid-Beta 1-40 Oligomers to Mature Fibrils through a Self-Catalytic Bimolecular Process
por: Morel, Bertrand, et al.
Publicado: (2021) -
Effects of Macromolecular
Crowding on Amyloid Beta
(16–22) Aggregation Using Coarse-Grained Simulations
por: Latshaw, David C., et al.
Publicado: (2014) -
Understanding how the crowded interior of cells stabilizes DNA/DNA and DNA/RNA hybrids–in silico predictions and in vitro evidence
por: Harve, Karthik S., et al.
Publicado: (2010)