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Chitosan-Based Self-Healing Hydrogel: From Fabrication to Biomedical Application
Biocompatible self-healing hydrogels are new-generation smart soft materials that hold great promise in biomedical fields. Chitosan-based self-healing hydrogels, mainly prepared via dynamic imine bonds, have attracted broad attention due to their mild preparation conditions, excellent biocompatibili...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535505/ https://www.ncbi.nlm.nih.gov/pubmed/37765622 http://dx.doi.org/10.3390/polym15183768 |
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author | Pan, Siyu Zhu, Chongyu Wu, Yuwei Tao, Lei |
author_facet | Pan, Siyu Zhu, Chongyu Wu, Yuwei Tao, Lei |
author_sort | Pan, Siyu |
collection | PubMed |
description | Biocompatible self-healing hydrogels are new-generation smart soft materials that hold great promise in biomedical fields. Chitosan-based self-healing hydrogels, mainly prepared via dynamic imine bonds, have attracted broad attention due to their mild preparation conditions, excellent biocompatibility, and self-recovery ability under a physiological environment. In this review, we present a comprehensive overview of the design and fabrication of chitosan-based self-healing hydrogels, and summarize their biomedical applications in tissue regeneration, customized drug delivery, smart biosensors, and three/four dimensional (3D/4D) printing. Finally, we will discuss the challenges and future perspectives for the development of chitosan-based self-healing hydrogels in the biomedical field. |
format | Online Article Text |
id | pubmed-10535505 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-105355052023-09-29 Chitosan-Based Self-Healing Hydrogel: From Fabrication to Biomedical Application Pan, Siyu Zhu, Chongyu Wu, Yuwei Tao, Lei Polymers (Basel) Review Biocompatible self-healing hydrogels are new-generation smart soft materials that hold great promise in biomedical fields. Chitosan-based self-healing hydrogels, mainly prepared via dynamic imine bonds, have attracted broad attention due to their mild preparation conditions, excellent biocompatibility, and self-recovery ability under a physiological environment. In this review, we present a comprehensive overview of the design and fabrication of chitosan-based self-healing hydrogels, and summarize their biomedical applications in tissue regeneration, customized drug delivery, smart biosensors, and three/four dimensional (3D/4D) printing. Finally, we will discuss the challenges and future perspectives for the development of chitosan-based self-healing hydrogels in the biomedical field. MDPI 2023-09-14 /pmc/articles/PMC10535505/ /pubmed/37765622 http://dx.doi.org/10.3390/polym15183768 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Pan, Siyu Zhu, Chongyu Wu, Yuwei Tao, Lei Chitosan-Based Self-Healing Hydrogel: From Fabrication to Biomedical Application |
title | Chitosan-Based Self-Healing Hydrogel: From Fabrication to Biomedical Application |
title_full | Chitosan-Based Self-Healing Hydrogel: From Fabrication to Biomedical Application |
title_fullStr | Chitosan-Based Self-Healing Hydrogel: From Fabrication to Biomedical Application |
title_full_unstemmed | Chitosan-Based Self-Healing Hydrogel: From Fabrication to Biomedical Application |
title_short | Chitosan-Based Self-Healing Hydrogel: From Fabrication to Biomedical Application |
title_sort | chitosan-based self-healing hydrogel: from fabrication to biomedical application |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535505/ https://www.ncbi.nlm.nih.gov/pubmed/37765622 http://dx.doi.org/10.3390/polym15183768 |
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