Cargando…
SARS-CoV-2-Specific CD8(+) T-Cells in Blood but Not in the Lungs of Vaccinated K18-hACE2 Mice after Infection
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 enters the host by infecting nasal ciliated cells. Then, the virus can spread towards the oropharyngeal cavity and the pulmonary tissues. The antiviral adaptive immunity is promptly induced in response to the virus’s detection, with virus-sp...
Autores principales: | Ferrantelli, Flavia, Manfredi, Francesco, Chiozzini, Chiara, Leone, Patrizia, Pugliese, Katherina, Spada, Massimo, Di Virgilio, Antonio, Giovannelli, Andrea, Valeri, Mauro, Cara, Andrea, Michelini, Zuleika, Andreotti, Mauro, Federico, Maurizio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535545/ https://www.ncbi.nlm.nih.gov/pubmed/37766110 http://dx.doi.org/10.3390/vaccines11091433 |
Ejemplares similares
-
Antiviral effect of SARS-CoV-2 N-specific CD8(+) T cells induced in lungs by engineered extracellular vesicles
por: Manfredi, Francesco, et al.
Publicado: (2023) -
Strong SARS-CoV-2 N-Specific CD8(+) T Immunity Induced by Engineered Extracellular Vesicles Associates with Protection from Lethal Infection in Mice
por: Ferrantelli, Flavia, et al.
Publicado: (2022) -
Simultaneous CD8(+) T-Cell Immune Response against SARS-Cov-2 S, M, and N Induced by Endogenously Engineered Extracellular Vesicles in Both Spleen and Lungs
por: Ferrantelli, Flavia, et al.
Publicado: (2021) -
Activation of Anti-SARS-CoV-2 Human CTLs by Extracellular Vesicles Engineered with the N Viral Protein
por: Manfredi, Francesco, et al.
Publicado: (2022) -
The C-Terminal Domain of Nef(mut) Is Dispensable for the CD8(+) T Cell Immunogenicity of In Vivo Engineered Extracellular Vesicles
por: Chiozzini, Chiara, et al.
Publicado: (2021)