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Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding
Rhabdomyosarcoma is a rare tumor that is diagnosed mostly in children and adolescents, rarely in adults, representing 2–5% of all soft tissue sarcomas. It has four subtypes that are recognized: embryonal (50%), alveolar (20%), pleomorphic (20%), and spindle cell/sclerosing (10%). The diagnosis of rh...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535666/ https://www.ncbi.nlm.nih.gov/pubmed/37763635 http://dx.doi.org/10.3390/medicina59091515 |
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author | Grigorean, Valentin Titus Serescu, Radu Anica, Andrei Coman, Violeta Elena Bedereag, Ştefan Iulian Sfetea, Roxana Corina Liţescu, Mircea Pleşea, Iancu Emil Florea, Costin George Burleanu, Cosmin Erchid, Anwar Coman, Ionuţ Simion |
author_facet | Grigorean, Valentin Titus Serescu, Radu Anica, Andrei Coman, Violeta Elena Bedereag, Ştefan Iulian Sfetea, Roxana Corina Liţescu, Mircea Pleşea, Iancu Emil Florea, Costin George Burleanu, Cosmin Erchid, Anwar Coman, Ionuţ Simion |
author_sort | Grigorean, Valentin Titus |
collection | PubMed |
description | Rhabdomyosarcoma is a rare tumor that is diagnosed mostly in children and adolescents, rarely in adults, representing 2–5% of all soft tissue sarcomas. It has four subtypes that are recognized: embryonal (50%), alveolar (20%), pleomorphic (20%), and spindle cell/sclerosing (10%). The diagnosis of rhabdomyosarcoma is based on the histological detection of rhabdomyoblasts and the expression of muscle-related biomarkers. Spindle cell/sclerosing rhabdomyosarcoma consists morphologically of fusiform cells with vesicular chromatin arranged in a storiform pattern or long fascicles, with occasional rhabdomyoblasts. Also, dense, collagenous, sclerotic stroma may be seen more commonly in adults. We present a rare case of an adult who presented to the hospital with a tumor in the left inguinal area, was first diagnosed with a left strangulated inguinal hernia and was operated on as an emergency, although the diagnosis was ultimately a spindle cell rhabdomyosarcoma of the inguinal region. |
format | Online Article Text |
id | pubmed-10535666 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-105356662023-09-29 Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding Grigorean, Valentin Titus Serescu, Radu Anica, Andrei Coman, Violeta Elena Bedereag, Ştefan Iulian Sfetea, Roxana Corina Liţescu, Mircea Pleşea, Iancu Emil Florea, Costin George Burleanu, Cosmin Erchid, Anwar Coman, Ionuţ Simion Medicina (Kaunas) Case Report Rhabdomyosarcoma is a rare tumor that is diagnosed mostly in children and adolescents, rarely in adults, representing 2–5% of all soft tissue sarcomas. It has four subtypes that are recognized: embryonal (50%), alveolar (20%), pleomorphic (20%), and spindle cell/sclerosing (10%). The diagnosis of rhabdomyosarcoma is based on the histological detection of rhabdomyoblasts and the expression of muscle-related biomarkers. Spindle cell/sclerosing rhabdomyosarcoma consists morphologically of fusiform cells with vesicular chromatin arranged in a storiform pattern or long fascicles, with occasional rhabdomyoblasts. Also, dense, collagenous, sclerotic stroma may be seen more commonly in adults. We present a rare case of an adult who presented to the hospital with a tumor in the left inguinal area, was first diagnosed with a left strangulated inguinal hernia and was operated on as an emergency, although the diagnosis was ultimately a spindle cell rhabdomyosarcoma of the inguinal region. MDPI 2023-08-23 /pmc/articles/PMC10535666/ /pubmed/37763635 http://dx.doi.org/10.3390/medicina59091515 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Grigorean, Valentin Titus Serescu, Radu Anica, Andrei Coman, Violeta Elena Bedereag, Ştefan Iulian Sfetea, Roxana Corina Liţescu, Mircea Pleşea, Iancu Emil Florea, Costin George Burleanu, Cosmin Erchid, Anwar Coman, Ionuţ Simion Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding |
title | Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding |
title_full | Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding |
title_fullStr | Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding |
title_full_unstemmed | Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding |
title_short | Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding |
title_sort | spindle cell rhabdomyosarcoma of the inguinal region mimicking a complicated hernia in the adult—an unexpected finding |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535666/ https://www.ncbi.nlm.nih.gov/pubmed/37763635 http://dx.doi.org/10.3390/medicina59091515 |
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