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Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding

Rhabdomyosarcoma is a rare tumor that is diagnosed mostly in children and adolescents, rarely in adults, representing 2–5% of all soft tissue sarcomas. It has four subtypes that are recognized: embryonal (50%), alveolar (20%), pleomorphic (20%), and spindle cell/sclerosing (10%). The diagnosis of rh...

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Autores principales: Grigorean, Valentin Titus, Serescu, Radu, Anica, Andrei, Coman, Violeta Elena, Bedereag, Ştefan Iulian, Sfetea, Roxana Corina, Liţescu, Mircea, Pleşea, Iancu Emil, Florea, Costin George, Burleanu, Cosmin, Erchid, Anwar, Coman, Ionuţ Simion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535666/
https://www.ncbi.nlm.nih.gov/pubmed/37763635
http://dx.doi.org/10.3390/medicina59091515
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author Grigorean, Valentin Titus
Serescu, Radu
Anica, Andrei
Coman, Violeta Elena
Bedereag, Ştefan Iulian
Sfetea, Roxana Corina
Liţescu, Mircea
Pleşea, Iancu Emil
Florea, Costin George
Burleanu, Cosmin
Erchid, Anwar
Coman, Ionuţ Simion
author_facet Grigorean, Valentin Titus
Serescu, Radu
Anica, Andrei
Coman, Violeta Elena
Bedereag, Ştefan Iulian
Sfetea, Roxana Corina
Liţescu, Mircea
Pleşea, Iancu Emil
Florea, Costin George
Burleanu, Cosmin
Erchid, Anwar
Coman, Ionuţ Simion
author_sort Grigorean, Valentin Titus
collection PubMed
description Rhabdomyosarcoma is a rare tumor that is diagnosed mostly in children and adolescents, rarely in adults, representing 2–5% of all soft tissue sarcomas. It has four subtypes that are recognized: embryonal (50%), alveolar (20%), pleomorphic (20%), and spindle cell/sclerosing (10%). The diagnosis of rhabdomyosarcoma is based on the histological detection of rhabdomyoblasts and the expression of muscle-related biomarkers. Spindle cell/sclerosing rhabdomyosarcoma consists morphologically of fusiform cells with vesicular chromatin arranged in a storiform pattern or long fascicles, with occasional rhabdomyoblasts. Also, dense, collagenous, sclerotic stroma may be seen more commonly in adults. We present a rare case of an adult who presented to the hospital with a tumor in the left inguinal area, was first diagnosed with a left strangulated inguinal hernia and was operated on as an emergency, although the diagnosis was ultimately a spindle cell rhabdomyosarcoma of the inguinal region.
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spelling pubmed-105356662023-09-29 Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding Grigorean, Valentin Titus Serescu, Radu Anica, Andrei Coman, Violeta Elena Bedereag, Ştefan Iulian Sfetea, Roxana Corina Liţescu, Mircea Pleşea, Iancu Emil Florea, Costin George Burleanu, Cosmin Erchid, Anwar Coman, Ionuţ Simion Medicina (Kaunas) Case Report Rhabdomyosarcoma is a rare tumor that is diagnosed mostly in children and adolescents, rarely in adults, representing 2–5% of all soft tissue sarcomas. It has four subtypes that are recognized: embryonal (50%), alveolar (20%), pleomorphic (20%), and spindle cell/sclerosing (10%). The diagnosis of rhabdomyosarcoma is based on the histological detection of rhabdomyoblasts and the expression of muscle-related biomarkers. Spindle cell/sclerosing rhabdomyosarcoma consists morphologically of fusiform cells with vesicular chromatin arranged in a storiform pattern or long fascicles, with occasional rhabdomyoblasts. Also, dense, collagenous, sclerotic stroma may be seen more commonly in adults. We present a rare case of an adult who presented to the hospital with a tumor in the left inguinal area, was first diagnosed with a left strangulated inguinal hernia and was operated on as an emergency, although the diagnosis was ultimately a spindle cell rhabdomyosarcoma of the inguinal region. MDPI 2023-08-23 /pmc/articles/PMC10535666/ /pubmed/37763635 http://dx.doi.org/10.3390/medicina59091515 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Grigorean, Valentin Titus
Serescu, Radu
Anica, Andrei
Coman, Violeta Elena
Bedereag, Ştefan Iulian
Sfetea, Roxana Corina
Liţescu, Mircea
Pleşea, Iancu Emil
Florea, Costin George
Burleanu, Cosmin
Erchid, Anwar
Coman, Ionuţ Simion
Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding
title Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding
title_full Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding
title_fullStr Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding
title_full_unstemmed Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding
title_short Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding
title_sort spindle cell rhabdomyosarcoma of the inguinal region mimicking a complicated hernia in the adult—an unexpected finding
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535666/
https://www.ncbi.nlm.nih.gov/pubmed/37763635
http://dx.doi.org/10.3390/medicina59091515
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