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MKL-1 suppresses ferroptosis by activating system Xc- and increasing glutathione synthesis

Chemotherapy is a standard method in traditional treatment for gastric cancer. It is well known that the anti-tumor effects of chemotherapy are achieved mainly through the direct killing of cancer cells via apoptosis. However, chemotherapy often fails due to drug resistance. Therefore, non-apoptotic...

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Detalles Bibliográficos
Autores principales: Dai, Zhou-Tong, Wu, Yong-Lin, Li, Xing-Rui, Liao, Xing-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535709/
https://www.ncbi.nlm.nih.gov/pubmed/37781038
http://dx.doi.org/10.7150/ijbs.80666