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Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes

Cancer is one of the leading causes of death worldwide. Because each person’s cancer may be unique, diagnosing and treating cancer is challenging. Advances in nanomedicine have made it possible to detect tumors and quickly investigate tumor cells at a cellular level in contrast to prior diagnostic t...

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Detalles Bibliográficos
Autores principales: Hamidu, Aisha, Pitt, William G., Husseini, Ghaleb A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535728/
https://www.ncbi.nlm.nih.gov/pubmed/37764594
http://dx.doi.org/10.3390/nano13182566
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author Hamidu, Aisha
Pitt, William G.
Husseini, Ghaleb A.
author_facet Hamidu, Aisha
Pitt, William G.
Husseini, Ghaleb A.
author_sort Hamidu, Aisha
collection PubMed
description Cancer is one of the leading causes of death worldwide. Because each person’s cancer may be unique, diagnosing and treating cancer is challenging. Advances in nanomedicine have made it possible to detect tumors and quickly investigate tumor cells at a cellular level in contrast to prior diagnostic techniques. Quantum dots (QDs) are functional nanoparticles reported to be useful for diagnosis. QDs are semiconducting tiny nanocrystals, 2–10 nm in diameter, with exceptional and useful optoelectronic properties that can be tailored to sensitively report on their environment. This review highlights these exceptional semiconducting QDs and their properties and synthesis methods when used in cancer diagnostics. The conjugation of reporting or binding molecules to the QD surface is discussed. This review summarizes the most recent advances in using QDs for in vitro imaging, in vivo imaging, and targeted drug delivery platforms in cancer applications.
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spelling pubmed-105357282023-09-29 Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes Hamidu, Aisha Pitt, William G. Husseini, Ghaleb A. Nanomaterials (Basel) Review Cancer is one of the leading causes of death worldwide. Because each person’s cancer may be unique, diagnosing and treating cancer is challenging. Advances in nanomedicine have made it possible to detect tumors and quickly investigate tumor cells at a cellular level in contrast to prior diagnostic techniques. Quantum dots (QDs) are functional nanoparticles reported to be useful for diagnosis. QDs are semiconducting tiny nanocrystals, 2–10 nm in diameter, with exceptional and useful optoelectronic properties that can be tailored to sensitively report on their environment. This review highlights these exceptional semiconducting QDs and their properties and synthesis methods when used in cancer diagnostics. The conjugation of reporting or binding molecules to the QD surface is discussed. This review summarizes the most recent advances in using QDs for in vitro imaging, in vivo imaging, and targeted drug delivery platforms in cancer applications. MDPI 2023-09-15 /pmc/articles/PMC10535728/ /pubmed/37764594 http://dx.doi.org/10.3390/nano13182566 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Hamidu, Aisha
Pitt, William G.
Husseini, Ghaleb A.
Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes
title Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes
title_full Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes
title_fullStr Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes
title_full_unstemmed Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes
title_short Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes
title_sort recent breakthroughs in using quantum dots for cancer imaging and drug delivery purposes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535728/
https://www.ncbi.nlm.nih.gov/pubmed/37764594
http://dx.doi.org/10.3390/nano13182566
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