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Translational Pharmacokinetic/Pharmacodynamic Modeling and Simulation of Oxaliplatin and Irinotecan in Colorectal Cancer

Despite the recent advances in this field, there are limited methods for translating organoid-based study results to clinical response. The goal of this study was to develop a pharmacokinetic/pharmacodynamic (PK/PD) model to facilitate the translation, using oxaliplatin and irinotecan treatments wit...

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Detalles Bibliográficos
Autores principales:	Zhu, Jinwei, Zhang, Yicui, Zhao, Yixin, Zhang, Jingwei, Hao, Kun, He, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535808/ https://www.ncbi.nlm.nih.gov/pubmed/37765243 http://dx.doi.org/10.3390/pharmaceutics15092274

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