Novel Thiazole-Based SIRT2 Inhibitors Discovered via Molecular Modelling Studies and Enzymatic Assays

Recently, the development of sirtuin small molecule inhibitors (SIRTIs) has been gaining attention for the treatment of different cancer types, but also to contrast neurodegenerative disease, diabetes, and autoimmune syndromes. In the search for SIRT2 modulators, the availability of several X-crysta...

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Detalles Bibliográficos
Autores principales: Abbotto, Elena, Casini, Beatrice, Piacente, Francesco, Scarano, Naomi, Cerri, Elena, Tonelli, Michele, Astigiano, Cecilia, Millo, Enrico, Sturla, Laura, Bruzzone, Santina, Cichero, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535842/
https://www.ncbi.nlm.nih.gov/pubmed/37765125
http://dx.doi.org/10.3390/ph16091316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535842/
https://www.ncbi.nlm.nih.gov/pubmed/37765125
http://dx.doi.org/10.3390/ph16091316

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