Targeting Autophagy, Apoptosis, and SIRT1/Nrf2 Axis with Topiramate Underlies Its Neuroprotective Effect against Cadmium-Evoked Cognitive Deficits in Rats

Cadmium is an environmental toxicant that instigates cognitive deficits with excessive glutamate excitatory neuroactivity in the brain. Topiramate, a glutamate receptor antagonist, has displayed favorable neuroprotection against epilepsy, cerebral ischemia, and Huntington’s disease; however, its eff...

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Detalles Bibliográficos
Autores principales: Arab, Hany H., Eid, Ahmed H., Yahia, Rania, Alsufyani, Shuruq E., Ashour, Ahmed M., El-Sheikh, Azza A. K., Darwish, Hany W., Saad, Muhammed A., Al-Shorbagy, Muhammad Y., Masoud, Marwa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535870/
https://www.ncbi.nlm.nih.gov/pubmed/37765022
http://dx.doi.org/10.3390/ph16091214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535870/
https://www.ncbi.nlm.nih.gov/pubmed/37765022
http://dx.doi.org/10.3390/ph16091214

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