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Caco-2 Cell Sheet Partially Laminated with HT29-MTX Cells as a Novel In Vitro Model of Gut Epithelium Drug Permeability

The intestinal epithelial Caco-2 cell monolayer is a well-established in vitro model useful for predicting intestinal drug absorption in humans. Coculture models of Caco-2 and goblet-cell-like HT29-MTX cells have been developed to overcome the lack of a mucus layer; however, those models are much le...

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Detalles Bibliográficos
Autores principales:	Cheng, Yi, Watanabe, Chie, Ando, Yusuke, Kitaoka, Satoshi, Egawa, Yuya, Takashima, Tomoya, Matsumoto, Akihiro, Murakami, Masahiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535880/ https://www.ncbi.nlm.nih.gov/pubmed/37765306 http://dx.doi.org/10.3390/pharmaceutics15092338

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