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Using the Correlation Intensity Index to Build a Model of Cardiotoxicity of Piperidine Derivatives

The assessment of cardiotoxicity is a persistent problem in medicinal chemistry. Quantitative structure–activity relationships (QSAR) are one possible way to build up models for cardiotoxicity. Here, we describe the results obtained with the Monte Carlo technique to develop hybrid optimal descriptor...

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Detalles Bibliográficos
Autores principales:	Toropova, Alla P., Toropov, Andrey A., Roncaglioni, Alessandra, Benfenati, Emilio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535953/ https://www.ncbi.nlm.nih.gov/pubmed/37764363 http://dx.doi.org/10.3390/molecules28186587

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