Synthesis and Biological Activity of Piperidinothiosemicarbazones Derived from Aminoazinecarbonitriles

To investigate how structural modifications affect tuberculostatic potency, we synthesized seven new piperidinothiosemicrabazone derivatives 8–14, in which three of them had a pyrazine ring replacing the pyridine ring. Derivatives 8–9 and 13–14 exhibited significant activity against the standard str...

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Detalles Bibliográficos
Autores principales: Ziembicka, Dagmara, Gobis, Katarzyna, Szczesio, Małgorzata, Augustynowicz-Kopeć, Ewa, Głogowska, Agnieszka, Korona-Głowniak, Izabela, Bojanowski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535983/
https://www.ncbi.nlm.nih.gov/pubmed/37765075
http://dx.doi.org/10.3390/ph16091267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535983/
https://www.ncbi.nlm.nih.gov/pubmed/37765075
http://dx.doi.org/10.3390/ph16091267

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