Chiral Aminoalcohol-Derived δ-Lactams Provide Easy Access to Piperidines and Acyclic Five-Carbon Building Blocks Bearing a Tertiary and a Quaternary Stereocenter

[Image: see text] A procedure for the synthesis of enantiopure piperidines and acyclic building blocks (5-aminopentanols, O-protected 5-hydroxypentanenitriles) containing a tertiary and a quaternary stereocenter has been developed. Starting from a phenylglycinol- or aminoindanol-derived δ-lactam bea...

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Detalles Bibliográficos
Autores principales: Llor, Núria, Peršolja, Peter, Calbó, Arnau, Ordeix, Sergi, Ramírez, Nicolás, Bosch, Joan, Amat, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536026/
https://www.ncbi.nlm.nih.gov/pubmed/37779970
http://dx.doi.org/10.1021/acsomega.3c03580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536026/
https://www.ncbi.nlm.nih.gov/pubmed/37779970
http://dx.doi.org/10.1021/acsomega.3c03580

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