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The Double-Leucine Motifs Affect Internalization, Stability, and Function of Organic Anion Transporting Polypeptide 1B1

Organic anion transporting polypeptide 1B1 (OATP1B1) is specifically expressed at the basolateral membrane of human hepatocytes and plays important roles in the uptake of various endogenous and exogenous compounds including many drugs. The proper functioning of OATP1B1, hence, is essential for the b...

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Detalles Bibliográficos
Autores principales: Wang, Xuyang, Chen, Jieru, Huang, Jiujiu, Hong, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536080/
https://www.ncbi.nlm.nih.gov/pubmed/37765248
http://dx.doi.org/10.3390/pharmaceutics15092279