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Multi-omics segregate different transcriptomic impacts of anti-IL-17A blockade on type 17 T-cells and regulatory immune cells in psoriasis skin

Durable psoriasis improvement has been reported in a subset of psoriasis patients after treatment withdrawal of biologics blocking IL-23/Type 17 T-cell (T17) autoimmune axis. However, it is not well understood if systemic blockade of the IL-23/T17 axis promotes immune tolerance in psoriasis skin. Th...

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Detalles Bibliográficos
Autores principales:	Kim, Jaehwan, Lee, Jongmi, Li, Xuan, Kunjravia, Norma, Rambhia, Darshna, Cueto, Inna, Kim, Katherine, Chaparala, Vasuma, Ko, Younhee, Garcet, Sandra, Zhou, Wei, Cao, Junyue, Krueger, James G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536146/ https://www.ncbi.nlm.nih.gov/pubmed/37781383 http://dx.doi.org/10.3389/fimmu.2023.1250504

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