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Liquid-liquid phase separation regulates alpha-synuclein aggregate and mitophagy in Parkinson’s disease
Parkinson’s disease (PD) is the second most common neurodegenerative disease in the world, and alpha-synuclein (α-syn) abnormal aggregate and mitochondrial dysfunction play a crucial role in its pathological development. Recent studies have revealed that proteins can form condensates through liquid–...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536155/ https://www.ncbi.nlm.nih.gov/pubmed/37781241 http://dx.doi.org/10.3389/fnins.2023.1250532 |