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Using Wastewater Surveillance to Monitor Gastrointestinal Pathogen Infections in the State of Oklahoma

During the COVID-19 pandemic, wastewater surveillance was widely used to monitor temporal and geographical infection trends. Using this as a foundation, a statewide program for routine wastewater monitoring of gastrointestinal pathogens was established in Oklahoma. The results from 18 months of surv...

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Autores principales: Kuhn, Katrin Gaardbo, Shukla, Rishabh, Mannell, Mike, Graves, Grant M., Miller, A. Caitlin, Vogel, Jason, Malloy, Kimberly, Deshpande, Gargi, Florea, Gabriel, Shelton, Kristen, Jeffries, Erin, De León, Kara B., Stevenson, Bradley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536226/
https://www.ncbi.nlm.nih.gov/pubmed/37764037
http://dx.doi.org/10.3390/microorganisms11092193
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author Kuhn, Katrin Gaardbo
Shukla, Rishabh
Mannell, Mike
Graves, Grant M.
Miller, A. Caitlin
Vogel, Jason
Malloy, Kimberly
Deshpande, Gargi
Florea, Gabriel
Shelton, Kristen
Jeffries, Erin
De León, Kara B.
Stevenson, Bradley
author_facet Kuhn, Katrin Gaardbo
Shukla, Rishabh
Mannell, Mike
Graves, Grant M.
Miller, A. Caitlin
Vogel, Jason
Malloy, Kimberly
Deshpande, Gargi
Florea, Gabriel
Shelton, Kristen
Jeffries, Erin
De León, Kara B.
Stevenson, Bradley
author_sort Kuhn, Katrin Gaardbo
collection PubMed
description During the COVID-19 pandemic, wastewater surveillance was widely used to monitor temporal and geographical infection trends. Using this as a foundation, a statewide program for routine wastewater monitoring of gastrointestinal pathogens was established in Oklahoma. The results from 18 months of surveillance showed that wastewater concentrations of Salmonella, Campylobacter, and norovirus exhibit similar seasonal patterns to those observed in reported human cases (F = 4–29, p < 0.05) and that wastewater can serve as an early warning tool for increases in cases, offering between one- and two-weeks lead time. Approximately one third of outbreak alerts in wastewater correlated in time with confirmed outbreaks of Salmonella or Campylobacter and our results further indicated that several outbreaks are likely to go undetected through the traditional surveillance approach currently in place. Better understanding of the true distribution and burden of gastrointestinal infections ultimately facilitates better disease prevention and control and reduces the overall socioeconomic and healthcare related impact of these pathogens. In this respect, wastewater represents a unique opportunity for monitoring infections in real-time, without the need for individual human testing. With increasing demands for sustainable and low-cost disease surveillance, the usefulness of wastewater as a long-term method for tracking infectious disease transmission is likely to become even more pronounced.
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spelling pubmed-105362262023-09-29 Using Wastewater Surveillance to Monitor Gastrointestinal Pathogen Infections in the State of Oklahoma Kuhn, Katrin Gaardbo Shukla, Rishabh Mannell, Mike Graves, Grant M. Miller, A. Caitlin Vogel, Jason Malloy, Kimberly Deshpande, Gargi Florea, Gabriel Shelton, Kristen Jeffries, Erin De León, Kara B. Stevenson, Bradley Microorganisms Article During the COVID-19 pandemic, wastewater surveillance was widely used to monitor temporal and geographical infection trends. Using this as a foundation, a statewide program for routine wastewater monitoring of gastrointestinal pathogens was established in Oklahoma. The results from 18 months of surveillance showed that wastewater concentrations of Salmonella, Campylobacter, and norovirus exhibit similar seasonal patterns to those observed in reported human cases (F = 4–29, p < 0.05) and that wastewater can serve as an early warning tool for increases in cases, offering between one- and two-weeks lead time. Approximately one third of outbreak alerts in wastewater correlated in time with confirmed outbreaks of Salmonella or Campylobacter and our results further indicated that several outbreaks are likely to go undetected through the traditional surveillance approach currently in place. Better understanding of the true distribution and burden of gastrointestinal infections ultimately facilitates better disease prevention and control and reduces the overall socioeconomic and healthcare related impact of these pathogens. In this respect, wastewater represents a unique opportunity for monitoring infections in real-time, without the need for individual human testing. With increasing demands for sustainable and low-cost disease surveillance, the usefulness of wastewater as a long-term method for tracking infectious disease transmission is likely to become even more pronounced. MDPI 2023-08-30 /pmc/articles/PMC10536226/ /pubmed/37764037 http://dx.doi.org/10.3390/microorganisms11092193 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kuhn, Katrin Gaardbo
Shukla, Rishabh
Mannell, Mike
Graves, Grant M.
Miller, A. Caitlin
Vogel, Jason
Malloy, Kimberly
Deshpande, Gargi
Florea, Gabriel
Shelton, Kristen
Jeffries, Erin
De León, Kara B.
Stevenson, Bradley
Using Wastewater Surveillance to Monitor Gastrointestinal Pathogen Infections in the State of Oklahoma
title Using Wastewater Surveillance to Monitor Gastrointestinal Pathogen Infections in the State of Oklahoma
title_full Using Wastewater Surveillance to Monitor Gastrointestinal Pathogen Infections in the State of Oklahoma
title_fullStr Using Wastewater Surveillance to Monitor Gastrointestinal Pathogen Infections in the State of Oklahoma
title_full_unstemmed Using Wastewater Surveillance to Monitor Gastrointestinal Pathogen Infections in the State of Oklahoma
title_short Using Wastewater Surveillance to Monitor Gastrointestinal Pathogen Infections in the State of Oklahoma
title_sort using wastewater surveillance to monitor gastrointestinal pathogen infections in the state of oklahoma
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536226/
https://www.ncbi.nlm.nih.gov/pubmed/37764037
http://dx.doi.org/10.3390/microorganisms11092193
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