Cargando…
Geometrical Characterisation of TiO(2)-rGO Field-Effect Transistor as a Platform for Biosensing Applications
The performance of the graphene-based field-effect transistor (FET) as a biosensor is based on the output drain current (I(d)). In this work, the signal-to-noise ratio (SNR) was investigated to obtain a high-performance device that produces a higher I(d) value. Using the finite element method, a nov...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536288/ https://www.ncbi.nlm.nih.gov/pubmed/37763827 http://dx.doi.org/10.3390/mi14091664 |
_version_ | 1785112830359371776 |
---|---|
author | Alim, Anis Amirah Roslan, Roharsyafinaz Nadzirah, Sh. Saidi, Lina Khalida Menon, P. Susthitha Aziah, Ismail Chang Fu, Dee Sulaiman, Siti Aishah Abdul Murad, Nor Azian Hamzah, Azrul Azlan |
author_facet | Alim, Anis Amirah Roslan, Roharsyafinaz Nadzirah, Sh. Saidi, Lina Khalida Menon, P. Susthitha Aziah, Ismail Chang Fu, Dee Sulaiman, Siti Aishah Abdul Murad, Nor Azian Hamzah, Azrul Azlan |
author_sort | Alim, Anis Amirah |
collection | PubMed |
description | The performance of the graphene-based field-effect transistor (FET) as a biosensor is based on the output drain current (I(d)). In this work, the signal-to-noise ratio (SNR) was investigated to obtain a high-performance device that produces a higher I(d) value. Using the finite element method, a novel top-gate FET was developed in a three-dimensional (3D) simulation model with the titanium dioxide-reduced graphene oxide (TiO(2)-rGO) nanocomposite as the transducer material, which acts as a platform for biosensing application. Using the Taguchi mixed-level method in Minitab software (Version 16.1.1), eighteen 3D models were designed based on an orthogonal array L(18) (6(1)3(4)), with five factors, and three and six levels. The parameters considered were the channel length, electrode length, electrode width, electrode thickness and electrode type. The device was fabricated using the conventional photolithography patterning technique and the metal lift-off method. The material was synthesised using the modified sol–gel method and spin-coated on top of the device. According to the results of the ANOVA, the channel length contributed the most, with 63.11%, indicating that it was the most significant factor in producing a higher I(d) value. The optimum condition for the highest I(d) value was at a channel length of 3 µm and an electrode size of 3 µm × 20 µm, with a thickness of 50 nm for the Ag electrode. The electrical measurement in both the simulation and experiment under optimal conditions showed a similar trend, and the difference between the curves was calculated to be 28.7%. Raman analyses were performed to validate the quality of TiO(2)-rGO. |
format | Online Article Text |
id | pubmed-10536288 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-105362882023-09-29 Geometrical Characterisation of TiO(2)-rGO Field-Effect Transistor as a Platform for Biosensing Applications Alim, Anis Amirah Roslan, Roharsyafinaz Nadzirah, Sh. Saidi, Lina Khalida Menon, P. Susthitha Aziah, Ismail Chang Fu, Dee Sulaiman, Siti Aishah Abdul Murad, Nor Azian Hamzah, Azrul Azlan Micromachines (Basel) Article The performance of the graphene-based field-effect transistor (FET) as a biosensor is based on the output drain current (I(d)). In this work, the signal-to-noise ratio (SNR) was investigated to obtain a high-performance device that produces a higher I(d) value. Using the finite element method, a novel top-gate FET was developed in a three-dimensional (3D) simulation model with the titanium dioxide-reduced graphene oxide (TiO(2)-rGO) nanocomposite as the transducer material, which acts as a platform for biosensing application. Using the Taguchi mixed-level method in Minitab software (Version 16.1.1), eighteen 3D models were designed based on an orthogonal array L(18) (6(1)3(4)), with five factors, and three and six levels. The parameters considered were the channel length, electrode length, electrode width, electrode thickness and electrode type. The device was fabricated using the conventional photolithography patterning technique and the metal lift-off method. The material was synthesised using the modified sol–gel method and spin-coated on top of the device. According to the results of the ANOVA, the channel length contributed the most, with 63.11%, indicating that it was the most significant factor in producing a higher I(d) value. The optimum condition for the highest I(d) value was at a channel length of 3 µm and an electrode size of 3 µm × 20 µm, with a thickness of 50 nm for the Ag electrode. The electrical measurement in both the simulation and experiment under optimal conditions showed a similar trend, and the difference between the curves was calculated to be 28.7%. Raman analyses were performed to validate the quality of TiO(2)-rGO. MDPI 2023-08-25 /pmc/articles/PMC10536288/ /pubmed/37763827 http://dx.doi.org/10.3390/mi14091664 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Alim, Anis Amirah Roslan, Roharsyafinaz Nadzirah, Sh. Saidi, Lina Khalida Menon, P. Susthitha Aziah, Ismail Chang Fu, Dee Sulaiman, Siti Aishah Abdul Murad, Nor Azian Hamzah, Azrul Azlan Geometrical Characterisation of TiO(2)-rGO Field-Effect Transistor as a Platform for Biosensing Applications |
title | Geometrical Characterisation of TiO(2)-rGO Field-Effect Transistor as a Platform for Biosensing Applications |
title_full | Geometrical Characterisation of TiO(2)-rGO Field-Effect Transistor as a Platform for Biosensing Applications |
title_fullStr | Geometrical Characterisation of TiO(2)-rGO Field-Effect Transistor as a Platform for Biosensing Applications |
title_full_unstemmed | Geometrical Characterisation of TiO(2)-rGO Field-Effect Transistor as a Platform for Biosensing Applications |
title_short | Geometrical Characterisation of TiO(2)-rGO Field-Effect Transistor as a Platform for Biosensing Applications |
title_sort | geometrical characterisation of tio(2)-rgo field-effect transistor as a platform for biosensing applications |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536288/ https://www.ncbi.nlm.nih.gov/pubmed/37763827 http://dx.doi.org/10.3390/mi14091664 |
work_keys_str_mv | AT alimanisamirah geometricalcharacterisationoftio2rgofieldeffecttransistorasaplatformforbiosensingapplications AT roslanroharsyafinaz geometricalcharacterisationoftio2rgofieldeffecttransistorasaplatformforbiosensingapplications AT nadzirahsh geometricalcharacterisationoftio2rgofieldeffecttransistorasaplatformforbiosensingapplications AT saidilinakhalida geometricalcharacterisationoftio2rgofieldeffecttransistorasaplatformforbiosensingapplications AT menonpsusthitha geometricalcharacterisationoftio2rgofieldeffecttransistorasaplatformforbiosensingapplications AT aziahismail geometricalcharacterisationoftio2rgofieldeffecttransistorasaplatformforbiosensingapplications AT changfudee geometricalcharacterisationoftio2rgofieldeffecttransistorasaplatformforbiosensingapplications AT sulaimansitiaishah geometricalcharacterisationoftio2rgofieldeffecttransistorasaplatformforbiosensingapplications AT abdulmuradnorazian geometricalcharacterisationoftio2rgofieldeffecttransistorasaplatformforbiosensingapplications AT hamzahazrulazlan geometricalcharacterisationoftio2rgofieldeffecttransistorasaplatformforbiosensingapplications |