Novel Tripodal Polyamine Tris-Pyrene: DNA/RNA Binding and Photodynamic Antiproliferative Activity

A novel tri-pyrene polyamine (TAL3PYR) bearing net five positive charges at biorelevant conditions revealed strong intramolecular interactions in aqueous medium between pyrenes, characterised by pronounced excimer fluorescence. A novel compound revealed strong binding to ds-DNA and ds-RNA, along wit...

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Detalles Bibliográficos
Autores principales: Jurković, Marta, Radić Stojković, Marijana, Božinović, Ksenija, Nestić, Davor, Majhen, Dragomira, Delgado-Pinar, Estefanía, Inclán, Mario, García-España, Enrique, Piantanida, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536304/
https://www.ncbi.nlm.nih.gov/pubmed/37765167
http://dx.doi.org/10.3390/pharmaceutics15092197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536304/
https://www.ncbi.nlm.nih.gov/pubmed/37765167
http://dx.doi.org/10.3390/pharmaceutics15092197

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