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A Species-Specific Anti-Human P2X7 Monoclonal Antibody Reduces Graft-versus-Host Disease in Humanised Mice

Graft-versus-host disease (GVHD) is a T cell-mediated inflammatory disorder that arises from allogeneic haematopoietic stem cell transplantation and is often fatal. The P2X7 receptor is an extracellular adenosine 5′-triphosphate-gated cation channel expressed on immune cells. Blockade of this recept...

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Detalles Bibliográficos
Autores principales:	Elhage, Amal, Cuthbertson, Peter, Sligar, Chloe, Watson, Debbie, Sluyter, Ronald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536354/ https://www.ncbi.nlm.nih.gov/pubmed/37765233 http://dx.doi.org/10.3390/pharmaceutics15092263

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