TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance?

Breast cancer is a major health concern worldwide, and resistance to therapies remains a significant challenge in treating this disease. In breast cancer, Transient Receptor Potential (TRP) channels are well studied and constitute key players in nearly all carcinogenesis hallmarks. Recently, they ha...

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Detalles Bibliográficos
Autores principales: Soussi, Mayar, Hasselsweiller, Alice, Gkika, Dimitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536409/
https://www.ncbi.nlm.nih.gov/pubmed/37755210
http://dx.doi.org/10.3390/membranes13090788
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author Soussi, Mayar
Hasselsweiller, Alice
Gkika, Dimitra
author_facet Soussi, Mayar
Hasselsweiller, Alice
Gkika, Dimitra
author_sort Soussi, Mayar
collection PubMed
description Breast cancer is a major health concern worldwide, and resistance to therapies remains a significant challenge in treating this disease. In breast cancer, Transient Receptor Potential (TRP) channels are well studied and constitute key players in nearly all carcinogenesis hallmarks. Recently, they have also emerged as important actors in resistance to therapy by modulating the response to various pharmaceutical agents. Targeting TRP channels may represent a promising approach to overcome resistance to therapies in breast cancer patients.
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spelling pubmed-105364092023-09-29 TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance? Soussi, Mayar Hasselsweiller, Alice Gkika, Dimitra Membranes (Basel) Review Breast cancer is a major health concern worldwide, and resistance to therapies remains a significant challenge in treating this disease. In breast cancer, Transient Receptor Potential (TRP) channels are well studied and constitute key players in nearly all carcinogenesis hallmarks. Recently, they have also emerged as important actors in resistance to therapy by modulating the response to various pharmaceutical agents. Targeting TRP channels may represent a promising approach to overcome resistance to therapies in breast cancer patients. MDPI 2023-09-12 /pmc/articles/PMC10536409/ /pubmed/37755210 http://dx.doi.org/10.3390/membranes13090788 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Soussi, Mayar
Hasselsweiller, Alice
Gkika, Dimitra
TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance?
title TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance?
title_full TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance?
title_fullStr TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance?
title_full_unstemmed TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance?
title_short TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance?
title_sort trp channels: the neglected culprits in breast cancer chemotherapy resistance?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536409/
https://www.ncbi.nlm.nih.gov/pubmed/37755210
http://dx.doi.org/10.3390/membranes13090788
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AT gkikadimitra trpchannelstheneglectedculpritsinbreastcancerchemotherapyresistance

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