Stereospecificity of Ginsenoside AD-1 and AD-2 Showed Anticancer Activity via Inducing Mitochondrial Dysfunction and Reactive Oxygen Species Mediate Cell Apoptosis

In this paper, the anti-cancer activity and molecular mechanisms of the isomers of AD-1 and AD-2 (20(R)-AD-1, 20(R)-AD-2, 20(S)-AD-1 and 20(S)-AD-2) were investigated. The results indicated that all of the four compounds obviously suppressed the viability of various cancer cells, and the anti-cancer...

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Detalles Bibliográficos
Autores principales: Wang, Xude, Ding, Meng, Zhao, Hong, Zhou, Mengru, Lu, Xuan, Sun, Yuanyuan, Zhang, Qinggao, Zhao, Yuqing, Wang, Ruoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536438/
https://www.ncbi.nlm.nih.gov/pubmed/37764474
http://dx.doi.org/10.3390/molecules28186698

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