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Sensitive HIV-1 DNA Pol Next-Generation Sequencing for the Characterisation of Archived Antiretroviral Drug Resistance

Modern HIV-1 treatment effectively suppresses viral amplification in people living with HIV. However, the persistence of HIV-1 DNA as proviruses integrated into the human genome remains the main barrier to achieving a cure. Next-generation sequencing (NGS) offers increased sensitivity for characteri...

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Detalles Bibliográficos
Autores principales: Botha, Johannes C., Byott, Matthew, Spyer, Moira J., Grant, Paul R., Gärtner, Kathleen, Chen, Wilson X., Burton, James, Bamford, Alasdair, Waters, Laura J., Giaquinto, Carlo, Turkova, Anna, Vavro, Cindy L., Nastouli, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536450/
https://www.ncbi.nlm.nih.gov/pubmed/37766218
http://dx.doi.org/10.3390/v15091811