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Metformin Hydrochloride Significantly Inhibits Rotavirus Infection in Caco2 Cell Line, Intestinal Organoids, and Mice
Rotavirus is one of the main pathogens that causes severe diarrhea in children under the age of 5, primarily infecting the enterocytes of the small intestine. Currently, there are no specific drugs available for oral rehydration and antiviral therapy targeting rotavirus. However, metformin hydrochlo...
Autores principales: | Zhang, Rui, Feng, Cui, Luo, Dandan, Zhao, Ruibo, Kannan, Perumal Ramesh, Yin, Yuebang, Iqbal, Muhammad Zubair, Hu, Yeting, Kong, Xiangdong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536476/ https://www.ncbi.nlm.nih.gov/pubmed/37765086 http://dx.doi.org/10.3390/ph16091279 |
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