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Metformin Hydrochloride Significantly Inhibits Rotavirus Infection in Caco2 Cell Line, Intestinal Organoids, and Mice

Rotavirus is one of the main pathogens that causes severe diarrhea in children under the age of 5, primarily infecting the enterocytes of the small intestine. Currently, there are no specific drugs available for oral rehydration and antiviral therapy targeting rotavirus. However, metformin hydrochlo...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Feng, Cui, Luo, Dandan, Zhao, Ruibo, Kannan, Perumal Ramesh, Yin, Yuebang, Iqbal, Muhammad Zubair, Hu, Yeting, Kong, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536476/
https://www.ncbi.nlm.nih.gov/pubmed/37765086
http://dx.doi.org/10.3390/ph16091279

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