Connexin-43 hemichannels orchestrate NOD-like receptor protein-3 (NLRP3) inflammasome activation and sterile inflammation in tubular injury

BACKGROUND: Without a viable cure, chronic kidney disease is a global health concern. Inflammatory damage in and around the renal tubules dictates disease severity and is contributed to by multiple cell types. Activated in response to danger associated molecular patterns (DAMPs) including ATP, the N...

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Detalles Bibliográficos
Autores principales: Roger, Elena, Chadjichristos, Christos E., Kavvadas, Panagiotis, Price, Gareth W., Cliff, Chelsy L., Hadjadj, Safia, Renciot, Jessy, Squires, Paul E., Hills, Claire E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536814/
https://www.ncbi.nlm.nih.gov/pubmed/37770948
http://dx.doi.org/10.1186/s12964-023-01245-7

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